Sorry, I cannot follow your meaning...
When will the settings left behind? You just delete the root folder and everything is gone...
The cache and some settings are not stored in the root folder! They are stored in the folders that
NANASEA mentioned above (in the %appdata% folders). If you run CSC Portable from a USB drive or a DVD, these folders are created on your system, thus the settings and cache are on the system and not on the USB or DVD. Keep in mind--
Portable. It can't be portable if the settings and cache are left behind. These folders and settings need to stay on the USB or DVD.
C:\Users\***\
AppData\Roaming\ComodoGroup\CSC
C:\Users\***\
AppData\Roaming\ComodoGroup\CSC\Cache\
These folders are created when CSC runs and they are not in the
root directory of CSC Portable.