Hm, at the moment, I've for
HIPS: 4155 Subkeys with 7869 values in the policy key
Firewall: 414 Subkeys with 1408 values in the policy key
And making any application "trusted" isn't a goog solution! Consider that trusted applications have far too much rights, which isn't needed for most applications. For example, trusted applications may access the complete registry by default - and this means also your D+ and Firewall settings! They may also access your system directories! Then you can also disable D+ completely...
Do you really trust all your applications? Can you be sure, that the programmers did all right and the application won't do anything, which ruins your setup?
Well making an app "trusted" is not always "bad" i agree you will "lose" some extra protection.
As i have run most of those apps for several months now and i know what they do, i had to chose between performance and security and i decided to "leave" a little security and gain a lot of performance.
So it's up to your personal feeling about trust and security if you decide to go with the 'trusted' apps or not.