do you mean “real time protection” when saying “automatic mode”?
That’s not recommended.
It’s not a problem with the databases, rather with the way those different engines are working by technical means.
There could be severe conflicts, including BSOD’S.
MBAM free and Emsisoft Emergency kit are rather fine choices. SAS not so much (these days), imho.
I’d really recommend you to use Kaspersky Virus Removal Tool (v. 11 atm) as an additional layer, i. e. scan-on-demand tool, just for reassuring. It’s a fine prog, just don’t forget to set it at it’s highest detection level.
Same goes for HIPS mostly (regarding incompabilities / abundance).
Maybe something like “Spyshelter free” (if on 32 bit, not working on 64 bit, though) and / or “Zemana free” (both good, but far from full capabilities) could prevent some nasty rare keyloggers going undetected by CIS from doing harm to your privacy. (Yet, Zemana seems to be somewhat loosely related to Google Inc., I’ve heard…)
Then (as you’re already using MBAM) there’s the free version of MalwareBytes Anti-Exploit (free version only giving protection to common browsers now)
Any “on-demand” scanner can be used with CIS. I use HitmanPro, TDSSKiller, MalwareBytes, and SuperAntiSpyware. If you are using CAV do NOT use another resident program unless it specifically states that it can be used with another resident AV.