Do you mean programs that can remove keyloggers or programs that can stop keyloggers from doing any harm?
Both if you have some spare time.
CIS (when properly configured) on a clean computer will protect you against keyloggers if you answer any popups correctly.
As for removing keyloggers I've got an article
(although it's still in Beta stage) that should allow you to clean an infected computer, at least pretty well.
Please let me know if you have any other questions.