One thing I noticed with this new version is a change to the monitoring of Windows events/hooks. In the previous version I had to untick this monitoring option in D+ in order to run the accessibility program ZoomText. I had never previously needed to do that, eitehr in v3.1 or v4.0. I am pleased to see that the latest version has fixed this issue so I can leave the monitoring of hooks enabled, improving security. ZoomText now runs without issues.
Great work Comodo, and much appreciated.