Every piece of software might cause problems for a small minority of people who use it This is because there is no way for developers to account for the myriads of other software and configurations present on the systems of the end users. Many many times the problems are due to incorrect configurations or incomplete uninstallations of other software. Other times there is malware or spyware at the root of a problem. I personally feel that the more paranoid you are and the more changes you make to Windows like turning off services and blocking elements, and also installing mostly needless "security enhancements", the more likely you are to have problems somewhere along the line. It's why I have learned to avoid most security forums like Wilder's and others. The great majority of Dragon's users, including me, have had absolutely no problems at all.
I wouldn't say that using security enhancements necessarily creates a higher risk of problems (perhaps a higher risk of inconvenience), but that using security enhancements without knowing exactly how they work and why they work in that way, might cause issues since the user has done something wrong or hasn't done anything at all when expected to do something. But then again we have bugs and such but I wouldn't say that they are specific to security enhancements.
May I ask what "needless" security enhancements are you implying at in this context? I've so far not come across any needless security enhancements in the situation where needless has it's original meaning.