I have finally got Comodo CIS 4 configured properly and must say I feel fairly secure on the Internet. I run CIS with firewall in custom policy mode and Defense+ in Safe mode.
Ran TestMyPC malware tests and scored 340/340.
Found some additionally keylogging, screen and clipboard capture tests at www.zemana.com
and Comodo caught all those.
A few comments.
CIS 4 in default configuration; i.e default firewall rules, is not very secure.
CIS 4 still needs work on Java exploits. Got nailed by one of those masquading as a Java Update.
Overall considering this is a free product, I think it is one of the best on the market.