May be the following is of help for you:
I fixed the problem. It was a clean update with a new fresh configuration. CIS proxy settings were empty. Also IE8 has empty proxy settings (and works great as well as CIS updater).
So I decided to make a full registry scan with RegScanner to find occurrences of proxy IP address used by cmdagent.exe. I've found some entries in HKEY_USERS and HKEY_CURRENT_CONFIG under Software/Microsoft/CurrentVersion (maybe paths were different, I can't remember them)
I deleted those two proxy entries in the registry and cmdagent.exe finally connected to the Comodo server :-)
Please tell developer to have a look at registry entries and look at where cmdagent.exe takes default proxy values in the registry repository.
Hope this thread could be be of help to comodo developers.
Best regards
Simon