IS it ok to run comodo D + with spyware terminator ( WITH HIPS ON)

I agree with EricHC, only use one HIPS. I use D+, not to say that ST hips is bad or D+ is better, don't know it's just my preference. ST has come a long way and I think the software is top of the line. I've been looking for an anti-malware product, free of cause, and installed a number of products to test and none is more robust then ST. It's not a resource hog, provides excellent malware protection, has real time monitoring protection, and the BIG ONE has automatic updates, which all the others fall short of. I run it along side of CIS and have no problems what so ever... What ever you do stay away from
IS360. There's a problem with it eating virtual memory. It does have real time monitoring but no auto update, makes no sense.