Comodo cannot be disabled by malware. Comodo just got voted #1 by Matousec. This behavior about security center happened to me with Online Armor and Threatfire.
Comodo can be disabled if the malware installs a driver. That's the reason for why IceSword is able to terminate CFP, because it installs a driver to do the job. But if you use common sense, and doesn't allow everything to install drivers, you'll be safe.
Vettetech
well I've just had a look at the WMI & can not see how to temporarily inactivate it prior to deleting the relevant folder (which I have found). Do I need to do this in safe mode plus administrator?
No, you'll only need to be on an administrator account.
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