Curious: why are there 2 instances of AcroRd32.exe and one of them has no icon? From my own ruleset I recall that those without the icons usually mean they're outdated executables or CFP rules that can and should be deleted.
The real concern is why you have such a long list of Firefox rules. Unless you have that many number of programs that launch it as the parent executables...Also, I assume you don't run a proxy server, otherwise you wouldn't have enabled the skip loopback connection checks per your above post. That being the case, there's no need for any incoming connection rules for Firefox or any browser - so delete those.explorer.exe
shouldn't need internet access at all. I recommend to block in and out on it.msiexec.exe
- this executable should only require outbound access as one-time occurrences only. There shouldn't be a need to allow them in Application Monitor. The fact that you have them in Application Monitor must prompt me to assume you enabled the "remember" option on the alerts. This option should only be enabled on programs that you know for sure would need or don't need internet access from hereon.
You have many other programs I don't know about. This could go on....hopefully you catch my drift on the type rules that should be created or not on different uses of programs.