When I have defense+ turned on... any games that launch in full screen will disable keyboard, mouse, and make the screen black... the only way out of it is to reset (power button power down doesnt work). Games that launch in windowed mode (or allow you to edit the launch file to make them windowed don't have this issue).
If i turn defense+ off (turn off permanently not just disable from the taskbar) then the games will launch with no issues.
i check the defense+ logs and nothing is mentioned... i also can't seem to find anything in the windows logs when this occurs either (it appears to freeze before anything gets logged perhaps?).
i am posting this here for the googlers of the world... when they have this issue they can disable defense+ (Open comodo click the Defense+ tab choose advanced choose Defense+ settings then checkmark the "deactivate the defense+ permanently then reboot) and the game should launch.
i am also posting this here for comodo... anyone have any ideas what a fix for this might be? i don't like trusting that there is no malicious code in every game i play... would prefer to have defense+ running

have a good day

info: video drivers are current nvidia drivers for a 9800gt (8.16.11.9107), machine is a quad core intel 4 gigs ram, windows 7 pro upgrade fresh install.
1.Change Defense+ mode > Training.
2.Change Firewall mode > Training.
3.run your game.
4.play your game for a while.
5.quit the game.
6.change defense+ and Firewall mode > default.
7.go to 'Network Security Policy' 'Computer Security Policy'
8.choose your game .exe file ex)dragonfly.exe
9.click 'Edit'>select 'Use a Predefined Policy'>Choose 'Trusted Application'
10.click 'Apply'
11.feel free with your game.
The key point is training mode.