What benefits will trust connect give me on wired networks? and what are its limitations if any?
TrustConnect prevents criminals from attacking or scanning your system from the local network (wired or wI-fi) that you're using to connect to the Internet.
Of course, the connection speed through the TrustConnect is lower than when connected directly, because it encrypts all of your traffic destined for the Internet.
Should I install it with CIS on my wired system?
We recommended you to use the both products: CIS and TrustConnect.
See more here:
https://www.comodo.com/trustconnect/faq_full.html#2.4