You may want to have another AntiVirus like
Avira AntiVir or
Avast! for
real-time scanning, and just have Comodo AV for
on-demand scanning.
Because it can be very bad to have two or more AV's running real-time scanning at the same time, we need to disable the real-time scanning in CAV before installing another AV.
Here's how:

Jeremy Bost.